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What is STENDRA (AVANAFIL)?

The medical drug STENDRA (AVANAFIL) is a modern and highly effective agent specifically developed for the treatment of erectile dysfunction in adult men. This medicinal product is available in the form of tablets for oral administration, which have a characteristic color and marking depending on the dosage. Thanks to its innovative formula, the drug ensures the fastest possible onset of action compared to many analogs of previous generations. The use of the latest technologies in pharmaceutical manufacturing guarantees a high safety profile and stable efficacy of each tablet.

From the perspective of clinical pharmacology, STENDRA (AVANAFIL) belongs to the group of selective inhibitors of phosphodiesterase type 5 (PDE-5). The action of this group of drugs is based on the ability to relax the smooth muscles of blood vessels, which significantly improves blood flow to the pelvic organs. It is important to understand that the pharmacological effect develops exclusively under the condition of natural sexual stimulation, which makes the process physiological. The drug is not a hormonal agent and does not affect the reproductive function or sperm quality of the patient.

The development and manufacture of this medicinal product are carried out by leading global pharmaceutical companies that adhere to the strictest Good Manufacturing Practice (GMP) quality standards. Each batch undergoes multi-stage control at all stages of creation, from checking raw materials to packaging the finished product. Thanks to this, patients receive a reliable medication that complies with all international protocols for the treatment of urological pathologies. The choice of this particular agent is often determined by its favorable tolerability profile and the speed of onset of the desired therapeutic effect.

What is STENDRA (AVANAFIL) prescribed for?

The main and only official indication for the use of STENDRA (AVANAFIL) is the treatment of erectile dysfunction in men. This condition is characterized by the inability to achieve or maintain an erection sufficient for a complete sexual intercourse. The medication works effectively regardless of the duration of the disease and the severity of the symptoms. Restoration of a normal physiological response occurs due to a powerful effect on the vascular system of the penis.

In addition to its direct physiological action, STENDRA (AVANAFIL) helps overcome the psychological barriers that often accompany potency problems. The return of self-confidence significantly reduces the level of anxiety and stress before intimacy. Improving the quality of sexual life positively affects the overall emotional state of a man and harmonizes partner relationships. Doctors note that successful therapy with this agent contributes to an overall increase in the quality of life of patients.

It is worth emphasizing that STENDRA (AVANAFIL) is not intended for use by healthy men for the purpose of artificial enhancement of sexual capabilities. The drug does not cause an artificial erection without corresponding sexual arousal, as its action is based on supporting the natural mechanisms of the body. Also, the agent does not protect against sexually transmitted diseases, so it is necessary to use appropriate barrier methods of contraception. Consultation with a specialized professional is a mandatory requirement before starting a course of therapy.

Composition and active ingredients of STENDRA (AVANAFIL)

The main active substance of STENDRA (AVANAFIL) is the avanafil molecule, which is characterized by high selectivity of action. This active component purposefully blocks the PDE-5 enzyme, minimizing the effect on other types of phosphodiesterase in the body. This exact selectivity ensures fewer side effects compared to first-generation drugs. The mechanism of action consists in the release of nitric oxide, which leads to the dilation of blood vessels and a powerful flow of blood to the corpora cavernosa.

Excipients in the composition of STENDRA (AVANAFIL) tablets play the role of stabilizers and ensure the proper release of the active substance in the gastrointestinal tract. Among them are mannitol, crospovidone, magnesium stearate, and other excipients, which are absolutely safe for the body. The tablet coating protects it from premature dissolution and facilitates the swallowing process. None of the auxiliary elements has its own pharmacological activity or affects the therapeutic effect of the medication.

Dosage of STENDRA (AVANAFIL)

The standard recommended dosage of STENDRA (AVANAFIL) for most patients is 100 mg, taken as needed. Depending on individual efficacy and tolerability, the dose can be increased to a maximum of 200 mg, or decreased to a minimum of 50 mg. The decision to change the dosage must be made exclusively by a doctor based on the clinical picture and the body's reaction. Exceeding the maximum daily dose on your own is dangerous and can lead to serious complications.

The frequency of taking STENDRA (AVANAFIL) should not exceed once a day (24 hours). The drug is not intended for daily continuous use in the absence of planned sexual activity. Patients with mild or moderate renal or hepatic impairment usually do not require dose adjustment, but treatment should be started with the minimum values. For elderly patients, the initial dose is also selected individually, taking into account concomitant diseases.

How to take STENDRA (AVANAFIL) correctly?

To achieve the optimal result, the STENDRA (AVANAFIL) tablet should be swallowed whole, washed down with a sufficient amount of clean non-carbonated water. It is recommended to take the drug approximately 15-30 minutes before the intended sexual activity, as it acts very quickly. The medication can be taken both on an empty stomach and with food, which makes its use extremely convenient. However, eating very fatty food can somewhat slow down the absorption process of the active substance and delay the onset of the effect.

We emphasize the importance of medical supervision: before starting the intake, be sure to consult a doctor to rule out hidden cardiovascular pathologies. It is necessary to keep in mind the individual reaction of the body, which can change depending on physical condition, stress, or fatigue. If you missed a planned dose, you do not need to take a double dose, just take a tablet before the next sexual intercourse. Never combine this agent with other drugs for the treatment of erectile dysfunction without direct instructions from a urologist.

Side effects of STENDRA (AVANAFIL)

Like any powerful drug, STENDRA (AVANAFIL) can cause certain undesirable reactions, although they do not occur in all patients. The most common side effects are headache, facial flushing due to vasodilation, and nasal congestion. Usually, these symptoms are mild or moderate in nature and disappear on their own within a few hours after administration. They are a consequence of the normal pharmacological action of the drug on the body's vascular bed.

Rare but serious side effects when using STENDRA (AVANAFIL) include dizziness, visual impairment, back pain, and rapid heartbeat. In exceptional cases, priapism can occur — a prolonged and painful erection that does not go away for more than 4 hours. If such a condition occurs, or in case of a sudden loss of vision or hearing, you must immediately seek emergency medical assistance. Timely medical attention will help avoid irreversible damage to the tissues of the penis.

Contraindications of STENDRA (AVANAFIL)

An absolute contraindication to the use of STENDRA (AVANAFIL) is the simultaneous intake of any forms of organic nitrates or nitric oxide donors. Such a combination can lead to a critical and life-threatening drop in blood pressure. Also, the agent is strictly prohibited for patients with severe heart failure, unstable angina, or those who have recently suffered a myocardial infarction or stroke. Individual hypersensitivity to avanafil or any auxiliary component also excludes the possibility of using this medicine.

STENDRA (AVANAFIL) is not intended for use by women and persons under 18 years of age, as its safety and efficacy for these groups have not been studied. With extreme caution, the agent is prescribed to patients with anatomical deformations of the penis or diseases that predispose to the development of priapism (for example, sickle cell anemia or leukemia). Elderly patients and individuals with severe renal or hepatic impairment must be under close medical supervision during therapy.

Interaction of STENDRA (AVANAFIL) with other drugs and alcohol

The clinical efficacy and safety of STENDRA (AVANAFIL) largely depend on the parallel intake of other medications. Concomitant use with alpha-blockers (drugs for the treatment of hypertension and prostate adenoma) requires caution due to the risk of symptomatic hypotension. Powerful inhibitors of the CYP3A4 enzyme, such as ketoconazole, ritonavir, or erythromycin, can significantly increase the concentration of avanafil in the blood. In such cases, the doctor usually prescribes the minimum dose of the drug or recommends temporarily abstaining from taking it.

As for compatibility with alcohol, STENDRA (AVANAFIL) allows the consumption of small doses of alcoholic beverages (for example, 1-2 glasses of wine). However, excessive alcohol consumption in combination with the drug can increase the risk of lowering blood pressure, cause dizziness, and rapid heartbeat. In addition, large doses of alcohol themselves negatively affect the ability to get an erection, neutralizing the therapeutic effect of the medicine. Since the drug can cause dizziness, patients should check their individual reaction before driving a vehicle or operating complex mechanisms.

Where to buy STENDRA (AVANAFIL) in Ukraine

You can purchase the original drug STENDRA (AVANAFIL) in Ukraine in licensed pharmacy chains with a prescription from a doctor. Many modern pharmacies offer an online booking service, which allows you to check the availability of the required dosage and secure the price before your visit. It is necessary to store the medication in its original packaging at room temperature, out of reach of children and protected from direct sunlight. Avoid purchasing on doubtful websites without appropriate licenses to guarantee receiving a safe and effective medicinal product.